4 edition of Human kallikrein 13 found in the catalog.
Human kallikrein 13
Thesis (M.Sc.) -- University of Toronto, 2003.
|Series||Canadian theses = -- Thèses canadiennes|
|The Physical Object|
|Pagination||2 microfiches : negative.|
Human kallikrein-related peptidases (KLKs) are (chymo)-trypsin-like serine proteinases that are expressed in a variety of tissues such as prostate, ovary, breast, testis, brain, and skin. Although their physiological functions have been only partly elucidated, many of the KLKs appear to be useful prognostic cancer markers, showing distinct. DJ, Yousef GM, et al. The spectrum of human kallikrein 6 (zyme/protease m/neurosin) expression in human tissues as assessed by immunohistochemistry. J Histochem Cytochem ; – Petraki CD, Karavana VN, Diamandis EP. Human kallikrein 13 expression in normal tissues: an immunohistochemical by:
Human kallikrein1(KLK1), also known as tissue kallikrein, is functionally conserved in its capacity to cleave the low molecular weight kininogen to release the vasoactive peptide, Lys-bradykinin which plays a role in regulating vasodilation, blood pressure reduction, smooth muscle relaxation and contraction, pain induction and inflammation.5/5(6). The human kallikrein-related peptidases are a subgroup of trypsin and chymotrypsin-like serine peptidases that are characterized by their homology to tissue kallikrein or kallikrein 1 (KLK1) encoded by the KLK1 gene (reviewed in).Cited by: 1.
hK1 - Human Kallikrein 1. Looking for abbreviations of hK1? It is Human Kallikrein 1. Human Kallikrein 1 listed as hK1. Human Kallikrein-Binding Protein; Human Kappa Opioid Receptor; Human Keratin 1; Human Keratin 10 Gene; Human Keratinocyte Growth Factor;. Human Kallikrein Production and Purification of Recombinant Protein and Monoclonal and Polyclonal Antibodies, and Development of a Sensitive and Specific Immunofluorometric Assay Clinical Chemistry, Vol Issue 1, 1 January , Pages –, https: Book, Software, and Web Site Reviews. Jacobs & DeMott Laboratory Test.
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Kallikrein-related peptidases are targets of active investigation by drug researchers as possible biomarkers for cancer.   Prostate-specific antigen (PSA; hk3, human kallikrein gene 3) and human glandular kallikrein (hK2) are used as tumor markers for prostate cancer.
The gene encoding human kallikrein-related peptidase 13 (KLK13), previously known as kallikrein-like gene 4 (KLK-L4) , is defined as a kallikrein-like gene based on structural homology, as well as chromosomal localization, and was originally isolated using the positional candidate gene approach .
Development of Chemical Tools to Monitor Human Kallikrein 13 (KLK13) Activity Article (PDF Available) in International Journal of Molecular Sciences 20(7) March with Reads. : Recombinant Human Kallikrein 13 Protein: Industrial & Scientific. Skip to main content.
Try Prime EN Hello, Sign in Account & Lists Sign in Account & Lists Orders Try Prime Cart. Industrial & Scientific. Go Search Best Sellers Gift Ideas New. Kallikrein 13 (KLK13) was first identified as an enzyme that is downregulated in a subset of breast tumors.
This serine protease has since been implicated in a number of pathological processes including ovarian, lung and gastric cancers. Here we report the design, synthesis and deconvolution of libraries of internally quenched fluorogenic peptide substrates to determine the specificity of Cited by: 3.
The Kallikrein 13 Recombinant Protein Antigen from Novus Biologicals is derived from E. coli. The Kallikrein 13 Recombinant Protein Antigen has been validated for the following applications: Antibody : ml Source: E.
coli Species Reactivity: Human Applications: Antibody Competition. Human glandular kallikrein 2 (hK2) is a prostate-specific kallikrein (produced by the prostatic epithelium with approximately 80% DNA sequence homology with PSA) that is emerging as a potential adjunct to PSA as a prostate cancer tumor marker.
1 In contrast to PSA, hK2 is a potent protease, with more t times the activity of the Cited by: 3. 13 References. Quantikine Human Kallikrein 3/PSA ELISA Kit(DKK). Sensitivity: ng/mL. Validated for Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma.
High precision and reproducibility. View product details.5/5(1). The crystal structure of the mouse glandular kallikrein (prorenin converting enzyme). Protein Sci., 6, – () PubMed CrossRef Google Scholar . In homeostasis, human kallikrein 13 (KLK13) is primarily expressed in the testis, prostate, breast, salivary glands, esophagus and the cervix [9,10,11,12] and is associated with certain skin pathologies, including psoriasis vulgaris and atopic dermatitis .Moreover, KLK13 is expressed at high levels in some types of salivary gland tumors .
Cited by: 3. Human kallikrein 13 (hK13; encoded by the KLK13 gene) is a secreted serine protease expressed in endocrine tissues, including the prostate, testis, breast, and ovary. We have previously reported steroid hormone regulation of the KLK13 gene and its clinical value as a marker of favorable prognosis in breast cancer at the mRNA level.
We hypothesized that hK13 may represent a potential Cited by: Recombinant Human Kallikrein 13 is produced by our Mammalian expression system and the target gene encoding GlyIle is expressed with a 6His tag at the C-terminus.
The construction of the first detailed map of the human kallikrein gene locus (13, 67, 68) allows for a more rational assignment of official gene symbols.
Since the rodent and other animal species kallikrein multigene families were known beforean international working party had reached agreement in on uniform nomenclature of the Cited by: The human kallikrein 13 protein (hK13) is expressed in many normal tissues.
Petraki et al have previously described presence of hK13 in salivary gland tissue, localized to duct epithelia and some. Cite this entry as: () Human Kallikrein 3.
In: Schwab M. (eds) Encyclopedia of Cancer. Springer, Berlin, Background: Kallikrein Human tissue kallikreins refer to a group of secreted serine proteases that are encoded by homologous genes clustering on chromosome 19q As a member of this family, human tissue Kallikrein 14 (hKLK14) is present in many tissues.
KLK7 kallikrein related peptidase 7 [ (human)] Gene ID:updated on Mar Summary. This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer.
human kallikrein 7 may have a role in breast carcnoma. Human kallikrein related peptidases 6 and 13 in combination with CA is a more sensitive test for ovarian cancer than CA alone For editorial issues, permissions, book requests, submissions and proceedings, contact the Amsterdam office [email protected] Asia.
Inspirees International (China Office)Cited by: This video is about "Kinin–kallikrein system". This video series is something special.
We're fully delving into all things everything and all things about the. Kallikrein-related peptidases, formerly named human tis-sue kallikreins (hKs), belong to a subgroup of the chy-motrypsin-like serine proteinase family S1A of clan PA(S) (Yousef and Diamandis, ; Barrett et al., ; Cle-ments et al., ).
The 15 human KLK genes are located on chromosome 19q and constitute the largest con. Kalikrein 8 (ECKLK8, PRSS19, ljudski kalikrein 8, hK8, mK8, ovasin, tumor-asocirani diferenciono izraženi TADG, NP, neuropsin) je enzim.
Ovaj enzim katalizuje sledeću hemijsku reakciju. Razlaganje amidnih supstrata koji slede bazne aminokiseline Arg ili Lys u P1 poziciji, sa preferencijom za Arg u odnosu na Lys. Ovaj enzim se aktivira odstranjivanjem N-terminalnog BRENDA: BRENDA entry.Contact Information.
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